Antibiogram of Uropathogenic Bacterial Isolates from Urine Samples

Muhammad Ahsan Ali Rana*, Asmara Imtiaz, Kiran Ahmad, Iqra Shafiq

  • Muhammad Ahsan rana 1. Department of Zoology, University of the Punjab, Lahore
  • Asmara Imtiaz 2. Department of Biology, Lahore Garrison University, Lahore, Pakistan
  • Kiran Ahmad 2. Department of Biology, Lahore Garrison University, Lahore, Pakistan
  • Iqra Shafiq 2. Department of Biology, Lahore Garrison University, Lahore, Pakistan
DOI: https://doi.org/10.54692/lgujls.2019.0402109
Keywords: Antimicrobial resistance, Escherichia coli, Klebsiella pneumonia, gramnegative bacteria, Proteus mirabilis

Abstract

ABSTRACT:
Most of the bacteria of Enterobacteriaceae family are pathogenic and cause urinary tract infections, Pneumonia and diarrheal diseases. It was noticed that antimicrobials resistance of bacteria is increasing day by day that brought expanded healthcare costs due to morbidity and mortality from treatment failures. In the present study three of gram negative bacteria Escherichia coli, Klebsiella pneumoniae and Proteus mirabilis of Enterobacteriaceae family were considered. Antibiotic susceptibility of these bacteria was checked against clinical samples by Kirby Bauer test commonly known as disc diffusion method. Eleven commercially available antibiotics i.e. Fosmomycin (FOS), Imipenem (IMP), Tazobactum (TZP), Meropenem (MEM), Amikacin (AK), Tobramycin (TOB), Nnitrofurantoin (F), Doxycycline (DO), Norfloxacin (NOR), Gentamycin (CN), and Nalidixic Acid (NA) were used to check efficacy against selected microbes.
Comparison of results produced by these bacteria showed variability in resistance pattern as FOS>IPM>MEM>AK>F>F>TZP>CN>TOB>DO>NOR>NA. Fosmomycin, Imipenem, Amikacin and Meropenem were found as most effective one among all selected antibiotics

Published
2020-07-15
Issue
Vol. 4 No. 02 (2020): LGU Journal of Life Sciences
Section
Articles