Review on the Techniques for Early Diagnosis of Alzheimer’s Disease

Abstract

Alzheimer’s disease is a neurological condition in which there is rapid
deterioration of the brain and it affects around 50 million people globally. The most
obvious sign of Alzheimer’s is dementia which is primarily an affliction of old age.
Majority of the people presenting with dementia in old age are Alzheimer’s patients.
The symptoms of Alzheimer’s disease are debilitating and have the ability to utterly
disrupt a person's normal life. It is only discovered after this terrible disease has
destroyed all neurons, thus there is little chance to cure it or reverse the adverse
effects. There are two types of techniques for detecting Alzheimer's disease: invasive
and non-invasive techniques. Invasive method obtains data from the patient by
drawing a small amount of blood or performing a lumbar puncture, whereas noninvasive
method collects data using imaging techniques like MRI and CT scan.
Invasive technique, on the other hand, is thought to be a more accurate indicator of
Alzheimer's disease than non-invasive technique since it provides strong biomarkers.
Once Alzheimer's disease has progressed to its final stage, it is incurable. Treatment
is only viable when the disease is in its initial stages. Future treatments for
Alzheimer's disease will focus on the causative maladies of neurofibrillary tangles (ptau)
and senile plaques (A). The pathological traits connected to debilitating disease,
special protein, b proteins, are critical for future therapeutics.