Seroprevalence of Hepatitis B Virus Among Sex Workers and General Population in Bahawalpur
Muhammad Nabeel Amjad and Hafiz Mohsin Ali
ABSTRACT: Hepatitis B is a life-threatening disease of liver caused by Hepatitis B Virus (HBV). It is considered as a serious global risk infecting 25.7crores (257 million) people around the globe. This virus (HBV) is responsible for causing deaths of 887000 people in the world due to Hepatocellular carcinoma and cirrhosis. Keeping this in view, the study was designed to investigate the seroprevalence of HBV along its various risk factors in sex workers of Bahawalpur City. Present study was conducted in district hospital of the Bahawalpur city from year 2016 to 2017. Samples (n = 9370) from general population were randomly collected from different geographical areas of city. Convenience samples of 33 female sex workers were collected to check the incidence in sex workers. Initially, samples were screened by ICT and confirmed by direct ELISA and PCR. Out of 9370 samples 224 (2.39%) were found positive with HBV. PCR identification using PR2a primers reveled that out of 224, 148 were seriously infected and were recommended for immediate medication. Out of these 33 females sex workers 22 were found infected, with high prevalence of about 66.67%. Foremost reasons for transmission of virus were probably blood transfusions, piercing, unsafe sexual intercourse and poor hygiene conditions due to unawareness and low literacy rate. Further planning to control the dissemination of HBV infection includes mass level screening followed by awareness campaigns& workshops for the enhancement and betterment of livelihood principles and hygiene of locals.