A Review on the Techniques for Early Diagnosis of Alzheimer’s Disease

Maria Shahzadi, Bareera Saeed, Muhammad Azzam Khan, Amna Rashid , Muhammad Bilal, Roma Imtiaz, Tallat Anwar Faridi

Abstract

Alzheimer’s disease is a neurological condition in which there is rapid deterioration of the brain and it affects around 50 million people globally. The most obvious sign of Alzheimer’s is dementia which is primarily an affliction of old age. Majority of the people presenting with dementia in old age are Alzheimer’s patients. The symptoms of Alzheimer’s disease are debilitating and have the ability to utterly disrupt a person's normal life. It is only discovered after this terrible disease has destroyed all neurons, thus there is little chance to cure it or reverse the adverse effects. There are two types of techniques for detecting Alzheimer's disease: invasive and non-invasive techniques. Invasive method obtains data from the patient by
drawing a small amount of blood or performing a lumbar puncture, whereas noninvasive method collects data using imaging techniques like MRI and CT scan. Invasive technique, on the other hand, is thought to be a more accurate indicator of Alzheimer's disease than non-invasive technique since it provides strong biomarkers. Once Alzheimer's disease has progressed to its final stage, it is incurable. Treatment is only viable when the disease is in its initial stages. Future treatments for Alzheimer's disease will focus on the causative maladies of neurofibrillary tangles (ptau) and senile plaques (A). The pathological traits connected to debilitating disease, special protein, b proteins, are critical for future therapeutics