Impact of Aflatoxins Exposure on Human Health and its Management Strategies

Authors

  • Naseem Zahra Food and Biotechnology Research Centre, PCSIR Laboratories Complex, Ferozepur Road, Lahore-54600, Pakistan
  • Khalid Saeed Food and Biotechnology Research Centre, PCSIR Laboratories Complex, Ferozepur Road, Lahore-54600, Pakistan
  • Asma Saeed Food and Biotechnology Research Centre, PCSIR Laboratories Complex, Ferozepur Road, Lahore-54600, Pakistan
  • Khurram Shahzad Food and Biotechnology Research Centre, PCSIR Laboratories Complex, Ferozepur Road, Lahore-54600, Pakistan
  • Muhammad Hassan Raza Department of Biotechnology, COMSATS University Islamabad, Abbottabad Campus, KPK, Pakistan
  • Sabaz Ali Khan Department of Biotechnology, COMSATS University Islamabad, Abbottabad Campus, KPK, Pakistan
  • Faheem Hafeez Superior College Kamoke Campus, Mari Road Adnan Garden Kamoke

DOI:

https://doi.org/10.54692/lgujls.2023.0702258

Keywords:

Aflatoxin, toxic, ELISA, detection, prevention

Abstract

Aflatoxins are common contaminants in human food supplies that affects the world's developing economies. These are cosmopolitan in distribution and found everywhere in nature and can grow under drought, warm, and humid conditions. The aflatoxins are secondary metabolites and mostly found in feed and food products. These are oncogenic, mutagenic, and immunosuppressive in nature. On the basis of the aflatoxin producing fungi, the aflatoxins are roughly split into two distinct groups: those that penetrate in pre-harvest circumstances and those that are generated in post-harvest conditions. Aflatoxins exposure has great public health impact in economically developing nations and lot of research is taking place to reduce its harmful impacts; as a result, we need to establish preventive strategies that are feasible for these high-risk populations. This review provides in-depth information regarding the presence of aflatoxins, their analysis, and potentially harmful consequences on human health, as well as various detoxification approaches.

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Published

2023-06-15